Studying the effects of repetitive mild traumatic brain injury (TBI) on the progression of taupathy, as TBI is the most robust environmental risk factor for developing dementia

Examining how the in vivo physiology of the medial temporal lobe changes in tauopathy

Exploring the interplay of aging and genetic risk factors on tau pathogenesis and synaptic dysfunction

Understanding the impact of nutrition and metabolic factors on cognition and disease pathogenesis, to inform the development of translational interventions for improving cognition in persons with mild cognitive impairment