Research Snapshots

MBI’s Research Snapshots highlight recent discoveries made by MBI researchers.

Research Snapshots pair an impactful image from work in a researcher’s laboratory — often associated with a newly published manuscript — with a brief description of how the study has impacted the researcher’s field of study. Research Snapshots aim to make research discoveries more accessible for other scientists and the community as a whole.

If you are an MBI researcher and would like to have your research considered for this feature, please contact assistant director of communications Todd Taylor or science writer Michelle Koidin Jaffee.

June 10, 2021

Drs. Min Lin & Phillip Mackie

Stem cell study demonstrates novel insight into development of Parkinson’s.

colored scans of brain data

April 1, 2021

Drs. Robert Eisinger & Aysegul Gunduz

New research by UF neuroscientists shows that brain activity associated with reward processing takes place in two parts of the basil ganglia.

graphs displaying the results of the study

Feb. 17, 2021

Drs. Malú Tansey & Madelyn Houser

New research provides insight into how a variety of factors might be linked to the development of Parkinson’s disease.

Image of a graph showing p-d symptoms varied amongst groups

Feb. 4, 2021

Drs. Cara Croft & Todd Golde

Preclinical study shows potential to reverse pathological tau formations.

a graph showing different stages of disease

Jan. 25, 2021

Drs. Michael Sunshine & David Fuller

Electrical stimulation shows promise for restoring breathing after drug overdose, spinal cord injury in preclinical research.

An abstract diagram, showing a dummy model attahed to wires and lines to pills and a electro frequency recording device

Nov. 9, 2020

Dr. Paramita Chakrabarty & Tosha Williams

UF neuroscientists investigated whether accumulations of tau and alpha synuclein can interact to accelerate the appearance of “mixed pathologies” in mouse models.

Using transgenic mouse models of tauopathy and synucleinopathy, Williams et al., show that preformed fibrils of tau and α-synuclein protein can cross-seed each other efficiently in the brain.

November 2, 2020

Drs. Yona Levites & Marshall Goodwin

A new study lends insights into factors that could help predict the efficacy of gene therapies using a genetically engineered antibody to target abnormal tau proteins.

Levites web post

July 7, 2020

Drs. Garrett Smith & Thomas C. Foster

New study demonstrates an example of the brain’s ability to shift and utilize different neural circuits to perform a task in order to compensate for brain aging.

Foster RS image

June 16, 2020

Drs. Adam Woods & Joseph Gullett

A new study by UF neuroscientists suggests that white matter “free water,” or fluid unconstrained by brain tissue, could play an important role in the cognitive aging process.

White matter snapshot 1

May 13, 2020

Drs. Ron Cohen & Vaughn Bryant

A study led by UF neuroscientists demonstrated that individuals with past heavy alcohol use demonstrate functional connectivity differences in the brain.

Image of a brain with superimposed connection points over it

April 7, 2020

Dr. Aysegul Gunduz & Robert Eisinger

A team of UF neuroscientists compared beta dynamics in two Parkinson’s disease deep brain stimulation, or DBS, targets.

Graphs detailing: Processed LFP Signal; Patient-specific beta; count; duration; strength; and patient level

Sept. 5, 2019

Drs. Ashok Kumar & Thomas Foster

Examining the role of NMDA receptor hypofunction and redox sensitivity of hippocampal synaptic transmission during aging.

Kumar_Thomas_NMDA_post

Nov. 20, 2018

Drs. Michael Pace & David Borchelt

Study demonstrates that additional proteins misfold in the presence of neurodegenerative disease pathologies.

neurodegeneration common

Oct. 16, 2018

Jolie Barter & Dr. Thomas Foster

The role of epigenetics in the process of brain aging and age-related cognitive decline.

epigenetics 1

Sept. 18, 2018

Drs. Sara Jo Nixon & Linda Cottler

UF is part of the largest long-term study of brain development and health in children.

RS_ABCD

Aug. 26, 2018

Drs. Abbi Hernandez & Sara Burke

The vulnerability of particular brain regions in old age that are important for problem-solving and reasoning.

Hernandez fluorescence

AUG. 24, 2018

Drs. Ashok Kumar & Thomas Foster

The relationship between brain inflammation, long-term potentiation and aging.

Kumar snapshot