Jianping Huang » McKnight Brain Institute

MBI researchers use 3D models to evaluate immunotherapy treatment in glioblastoma and osteosarcoma

December 18, 2023

Dr. Jianping Huang and colleagues publish paper in the journal Acta Biomaterialia.

A very complex 3-D graphical image of a flat, red cube on top of a rainbow cube with an area marker 'tumor' within it. Here's a description of the figure from the paper: In Vitro Immunotherapy Assay (iVITA). A) brightfield image of type I collagen-conjugated LLS (COL1-LLS). B) Fluorescent image of COL1-LLS stained for anti-collagen antibody (green) confirms presence of the biomolecules on the surface of LLS. C) 3D view confocal image of iVITA platform showing dispersion of CAR T cells (green) around a tumor sphere in COL1-LLSRhB (red). D) Depth coded max IP 3D view of (C).

UF to test novel CAR-modified T-cell technique in clinical trial for glioblastoma

April 18, 2022

First-in-human trial aimed at enhancing effectiveness of immunotherapy against brain tumors.

Doctor huang and her team gather around in the lab to discuss test results

New study shows modified T cells enhance effectiveness of immunotherapy in tumors

October 18, 2019

New study led by Dr. Jianping Huang uses novel approach to halt or even shrink late-stage tumors such as glioblastoma, ovarian cancer and pancreatic cancer.