Jianping Huang » McKnight Brain Institute

First-in-human trial to test therapy for pediatric gliomas

August 7, 2025

Drs. Jianping Huang and John Ligon have launched a human clinical trial to test an immunotherapy treatment for children with high-grade gliomas.

MBI researchers use 3D models to evaluate immunotherapy treatment in glioblastoma and osteosarcoma

December 18, 2023

Dr. Jianping Huang and colleagues publish paper in the journal Acta Biomaterialia.

A very complex 3-D graphical image of a flat, red cube on top of a rainbow cube with an area marker 'tumor' within it. Here's a description of the figure from the paper: In Vitro Immunotherapy Assay (iVITA). A) brightfield image of type I collagen-conjugated LLS (COL1-LLS). B) Fluorescent image of COL1-LLS stained for anti-collagen antibody (green) confirms presence of the biomolecules on the surface of LLS. C) 3D view confocal image of iVITA platform showing dispersion of CAR T cells (green) around a tumor sphere in COL1-LLSRhB (red). D) Depth coded max IP 3D view of (C).

UF to test novel CAR-modified T-cell technique in clinical trial for glioblastoma

April 18, 2022

First-in-human trial aimed at enhancing effectiveness of immunotherapy against brain tumors.

Doctor huang and her team gather around in the lab to discuss test results

New study shows modified T cells enhance effectiveness of immunotherapy in tumors

October 18, 2019

New study led by Dr. Jianping Huang uses novel approach to halt or even shrink late-stage tumors such as glioblastoma, ovarian cancer and pancreatic cancer.